Randomised controlled trial of L-carnitine as a nutritional supplement in preterm infants

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Randomised controlled trial of L-carnitine as a nutritional supplement in preterm infants.

AIMS To evaluate the effect of L-carnitine supplementation (25 mg/kg/d) on the growth and incidence of hypoglycaemia in preterm infants. METHODS A double blind, placebo controlled randomised trial, stratified for gestational age, was conducted of 86 preterm infants between 28 and 34 gestational weeks. The median gestational ages in the carnitine group and placebo groups were 30.7 weeks (range...

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Weaning preterm infants: a randomised controlled trial.

OBJECTIVE To assess the effect on growth and iron status in preterm infants of a specially devised weaning strategy compared with current best practices in infant feeding. The preterm weaning strategy recommended the early onset of weaning and the use of foods with a higher energy and protein content than standard milk formula, and foods that are rich sources of iron and zinc. SUBJECTS AND DE...

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Randomised controlled trial of colloid infusions in hypotensive preterm infants.

Colloid infusions are often given to treat hypotension in preterm infants. The aim of this work was to assess whether it was the amount of protein or the volume of the colloid infused which accounted for the observed increase in blood pressure. Sixty preterm infants were randomised (20 in each group) to receive 5 ml/kg 20% albumin, 15 ml/kg fresh frozen plasma, or 15 ml/kg 4.5% albumin. All inf...

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Randomised controlled trial of cisapride in preterm infants.

AIM To determine the effect of cisapride on gastrointestinal motility in preterm infants. METHODS Cisapride (0.2 mg/kg, 8 hourly ) or placebo was given first for seven days in a double blind randomised crossover study of 10 preterm infants. Gastrointestinal motility was assessed on day 3 of each treatment. The half gastric emptying time (GET1/2) was determined by using ultrasonography to meas...

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Randomised controlled trial of cisapride in preterm infants

Aim—To determine the eVect of cisapride on gastrointestinal motility in preterm infants. Methods—Cisapride (0.2 mg/kg, 8 hourly ) or placebo was given first for seven days in a double blind randomised crossover study of 10 preterm infants. Gastrointestinal motility was assessed on day 3 of each treatment. The half gastric emptying time (GET1⁄2) was determined by using ultrasonography to measure...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood - Fetal and Neonatal Edition

سال: 1998

ISSN: 1359-2998,1468-2052

DOI: 10.1136/fn.78.3.f185